Midfielder, Kieron Parnaby, has joined Guisborough Town after a dual-registration deal was agreed.
Parnaby joined the Blues in the summer after impressing during a trial period during pre-season, however he now joins the Priorymen in search of more game time.
The youngster has managed to make several substitute appearances for the Blues so far this campaign, including scoring against Hednesford Town earlier this month.
Also departing is Dominic Furness, who has left the club by mutual consent. The midfielder has impresssed during his short spell with the club.
Strikers Ashley Coffey and Greg Rutherford are ruled out of the tie through injury. Coffey is yet to make an appearance for the Seasiders.
Goalkeeeper, Jack Norton is classed as a concern for the clash, as well as midfielder, David McTiernan who picked up an injury earlier on in the season.
In terms of the goalkeeping position, Daniel Dixon is returning to the matchday squad after a spell being unavailable due to other commitments.
There will be LIVE commentary from the South Kesteven Sports Stadium from 3pm on Yorkshire Coast Radio Extra.